Is Cararthron safe?
Cararthron’s ingredients have been designated as GRAS (Generally Recognized As Safe) according to strict FDA (Food and Drug Administration) standards. In clinical studies, Cararthron has been shown to have side effects comparable to placebo. To date, the number of side effects reported by physicians and patients about Cararthron has been less than 0.2%, significantly low compared to most other prescription products.
What is inhibition of two inflammatory pathways (COX-1/COX-2 & 5-LOX)?
This refers to Cararthron’s management of arachidonic acid (AA) metabolism across both the COX and LOX pathways to help restore a metabolic balance. This is especially important in the COX pathway composed of COX-1 and COX-2 where inhibition of either one over the other can result in gastric, renal, and cardiovascular problems. For example, inhibition of prostaglandins in COX-1 enzymatic conversion of AA necessary for gastric mucosal maintenance results in an increase in ulceration due to the production of leukotrienes that attract white blood cells to produce inflammatory which cause an ulcer. If one selectively inhibits the COX-2 enzymatic conversion of AA to prostacyclins, then thromboxanes from the COX-1 pathway dominate and vasoconstrict the arteries causing poor renal perfusion which can result in high blood pressure and peripheral edema.
There is also a “shunting” of AA metabolism down the LOX pathway where vasoconstrictive leukotrienes are generated further constricting arteries. Such selective inhibition and shunting of metabolism can also lead to cardiovascular complications. Cararthron provides inhibition management of LOX inflammatory metabolites in addition to balanced inhibition on COX-1 & COX-2 pathways.
Does Cararthron contain a recognized class of ingredients?
Cararthron contains a widely recognized class of polyphenol ingredients commonly referred to as flavonoids. These are natural compounds from plant-based food sources which are generally accepted to provide certain therapeutic benefits and are often found in many fruits, vegetables and nuts. The specific chemical structure of the primary constituent ingredients found in Cararthron are provided in Cararthron’s package insert. Flavonoids as a class can be found in most authoritative chemical and botanical reference materials.
How strong of an antioxidant is Cararthron?
Cararthron is a very strong antioxidant. When compared to Vitamin C and Vitamin E in oxygen radical absorbance capacity (ORAC) assays, an assay designed to measure the ability to “soak” up reactive oxygen species (ROS, also known as oxygen free radicals), Cararthron’s ingredient combination, flavocoxid, has a high ORAC value (~5,500). This value is higher than the comparable ORAC value of Vitamin C (~5,000) and Vitamin E (~1,100). Cararthron’s antioxidant potency is even significantly higher than that of blueberries and grapes, well-known sources of antioxidants. In terms of the metabolic process associated with osteoarthritis, the ability of a product to absorb oxygen free radicals can be beneficial to cartilage.
Should Cararthron be taken with or without other foods?
Taking Cararthron after meals increases the absorption of Cararthron’s key ingredients into the blood. We recommend that you take Cararthron with food.