Clinical Evidence
Scientific Validation for Our Products
Collagen Hydrolysate
- Collagen hydrolysate is of interest as a therapeutic agent of potential utility in the treatment of osteoarthritis and osteoporosis. Its high level of safety makes it attractive as an agent for long-term use in these chronic disorders. Semin Arthritis Rheum. 2000 Oct;30(2):87-99.
Read More - Oral Administration of 14C Labeled Gelatin Hydrolysate Leads to an Accumulation of Radioactivity in Cartilage of Mice. (Journal of Nutrition. 1999;129:1891-1895.)
Read More - Bioactive Collagen Peptides Stimulate the Regeneration of Cartilage Tissue.
Read More - Collagen hydrolysate for the treatment of osteoarthritis and other joint disorders: a review of the literature.
Read More - Stimulation of type II collagen biosynthesis and secretion in bovine chondrocytes cultured with degraded collagen.
Read More - 24-Week study on the use of collagen hydrolysate as a dietary supplement in athletes with activity-related joint pain.
Read More - Collagen Hydrolysate Improves Joint Function in Adults with Mild Symptoms of Osteoarthritis of the Knee.
Read More - Collagen hydrolysate intake increases skin collagen expression and suppresses matrix metalloproteinase 2 activity.
Read More - A new view concerning the effects of collagen hydrolysate intake on skin properties.
Read More - Differential effect of ECM molecules on re-expression of cartilaginous markers in near quiescent human chondrocytes.
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Hyaluronic Acid
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Aging fibroblasts resist phenotypic maturation because of impaired hyaluronan-dependent CD44/epidermal growth factor receptor signaling.
Read More - Absorption, uptake and tissue affinity of high-molecular-weight hyaluronan after oral administration in rats and dogs.
Read More - Hyaluronan facilitates transforming growth factor-beta1-mediated fibroblast proliferation.
Read More - Involvement of hyaluronan in regulation of fibroblast phenotype.
Read More - Effects of Pro-Hyp, a collagen hydrolysate-derived peptide, on hyaluronic acid synthesis using in vitro cultured synovium cells and oral ingestion of collagen hydrolysates in a guinea pig model of osteoarthritis.
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Chondroitin Sulphate
- Effect of chondroitin sulfate and hyaluronic acid on gene expression in a three-dimensional culture of chondrocytes.
Read More - Chondroitin sulphate reduces both cartilage volume loss and bone marrow lesions in knee osteoarthritis patients starting as early as 6 months after initiation of therapy: a randomised, double-blind, placebo-controlled pilot study using MRI.
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Boswellia
- Clinical evaluation of Boswellia serrata (Shallaki) resin in the management of Sandhivata (osteoarthritis).
Read More - Modulation of the immune system by Boswellia serrata extracts and boswellic acids.
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Turmeric (Curcumin)
- Curcumin: a novel therapeutic for burn pain and wound healing.
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Ginger (Zingiber officinale)
- Ayurvedic medicine offers a good alternative to glucosamine and celecoxib in the treatment of symptomatic knee osteoarthritis: a randomized, double-blind, controlled equivalence drug trial.
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Winter Cherry
- Cherry consumption and decreased risk of recurrent gout attacks.
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Cat’s Claw (Uncaria tomentosa)
- Anti-inflammatory activity of Mitraphylline isolated from Uncaria tomentosa bark.
Read More - Cat’s claw: an Amazonian vine decreases inflammation in osteoarthritis.
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